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Potential benefits on erectile performance may arise from glycemic controlrelated mechanisms, including inhibition of AGE generation and reduction of oxidative stress [179], as well as preservation of mitochondrial integrity via modulation of programmed cell death pathways, such as pyroptosis and ferroptosis [180,181]

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Semaglutide was developed based on GLP-1(7-37) backbone, its Lys side chain was modified with a long chain fatty acid, enabling it to bind to plasma albumin for slower drug release

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By the end of this article, you will gain insights into: The mechanisms by which GLP-1 receptor agonists operate