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PCa utilizes the citric acid cycle as a primary energy source as it does not follow the Warburg effect

Plus, more from The Bump: Uma Darji, MD, IBCLC, is a family physician and lactation consultant in Raleigh, North Carolina

Studies varied in treatment duration (acute infusion to 26 weeks), GLP-1 RA agents used (reflecting the medications available at the time of each study), stimulus categories examined, and analytic approaches employed

FDA Orange Book

NICE guidance (NG28) recommends considering GLP-1 receptor agonists for adults with type 2 diabetes when glycaemic targets are not achieved with other therapies, particularly in those with established cardiovascular disease or at high cardiovascular risk

| How the calculator works | Why we dont recommend counting | How to reach your target without counting | Why we cap deficits at 15% | Recalculating as you lose weight | Targets by medication | Factors that affect your needs | FAQs | Take home message To lose weight sustainably on GLP-1 medications while maintaining muscle mass, you should eat a calorie deficit of between 10-15%