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Impaired intestinal Akkermansia muciniphila and aryl hydrocarbon receptor ligands contribute to nonalcoholic fatty liver disease in mice

doi: 10.31083/j.rcm.2018.02.907

As these therapies move into broader use, addressing these real-world complexities will be essential to realizing their full potential

Stable cell lines were generated by the transient transfection of 150 cm 2 flasks of cells with pCDNA3.1 expression vectors using 15 g DNA complexed with 60 L Fugene-6 (Promega), according to manufacturer directions

Modern diets are often high in carbohydrates, causing blood sugar to spike and unused sugars to be stored as fat

Some rodent studies found that exenatide reduced oxycodone self-administration and heroin-seeking behaviors, while others reported minimal effects on morphine-related behaviors