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156 Authors in this writing group have observed in clinical practice the changes to food preferences and eating behaviors described here as follows: a substantial number of individuals are less interested in food

Reagents can be provided by and at Amgens sole discretion, pending scientific review and a completed material transfer agreement with Amgen

Possible concerns for older adults include: loss of bone or muscle mass (or both) if weight loss is too rapid or not paired with resistance exercise (also called strength training) nutrient deficiencies if their appetite decreases without balancing nutrition, which can worsen existing vitamin B12, vitamin D, and protein deficiencies dehydration, dizziness, or digestive system side effects (such as diarrhea), which may cause new or worsened health problems hypoglycemia (low blood sugar) or hypotension (low blood pressure), which can affect people already taking medications for these conditions increased heart rate or increased blood pressure, which may carry a higher risk in older adults who have heart disease or take heart medications Glucagon-like peptide-1 (GLP-1) receptor agonists are prescription drugs used for weight management and other conditions

Available at: 82 KeshavarzianAGreenSJEngenPAVoigtRMNaqibAForsythCBet al

Brand-Name Semaglutide FDA-approved (e.g., Wegovy, Ozempic) Standardized formulation with fixed dosing options Available only through a pharmacy Ideal for patients whose insurance covers brand-name prescriptions Compounded Semaglutide Custom-prepared by licensed compounding pharmacies Can be enhanced with supportive ingredients like L-Carnitine, which helps convert stored fat into energy, boosts metabolism, and supports exercise endurance Allows for more individualized dosing and adjustments, making it a better fit for patients who cannot tolerate brand-name semaglutide or want a more tailored approach Shipped directly to patients following provider approval How Treatment Works Regardless of which option you choose, treatment begins with a comprehensive consultation to determine candidacy

Strength training, such as lifting weights or using resistance bands, builds lean muscle
