glp 1 analog drugs glp-1_analogs [TUSOM GLP-1 Medications for Weight Loss:
Description
As a result, scientists are increasingly attempting to combine GLP-1 RAs with other hormone-based medications or engineer them as dual or triple receptor agonists to enhance their efficacy in treating obesity while mitigating side effects

iScience 24 , 116 (2021)

Consequently, it is essential to prioritize shared decision-making and individualized risk-benefit assessments for prescribing GLP-1 RAs, while avoiding misuse with off-label indications
Given the high disease burden of NASH and limited therapeutic options currently available, the FDA has proposed an accelerated pathway for drug approval

10 Pharmacists who are aware of cases of exenatide-associated acute pancreatitis or other serious adverse drug reactions are encouraged to report their findings to MedWatch, the FDAs adverse drug reporting program (www.fda.gov/Safety/MedWatch/ Anti-exenatide Antibodies: In phase III clinical trials, 41% to 49% of patients receiving exenatide developed anti-exenatide antibodies

Lancet 394(10193):121130
