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This approach is in line with guidelines and consensus statements from leading organizations, such as the American Diabetes Association, which advocate for integrated care in the management of diabetes and obesity, underscoring the significance of GLP-1 agonists in treating these interrelated conditions (American Diabetes Association, 2023)

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Our objectives were to compare incretin concentrations and rates of glucose production and gluconeogenesis in youth with type 2 diabetes before and after short-term metformin therapy compared with peers with normal glucose tolerance (NGT)