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.GLP-1R, GIPR, GCGR insulin/GCG , glucose metabolism,

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Compounded GLP has not been approved by the FDA for weight loss, but studies indicate potential benefits

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Zepbound's dual GLP-1/GIP mechanism curbs hunger 47% by day 7, delays gastric emptying, enhances fullness signals to the brain

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Despite the potential clinical benefits of GLP-1RA plus SGLT2i combination therapy in patients with T2DM, several factors may delay this combination to become a common practice soon, such as reimbursement and costs associated with polypharmacy

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