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GLP-1 receptor agonists , by substantially improving insulin sensitivity and reducing postprandial glucose excursions, lower the ambient insulin and IGF-1 environment effectively reducing a critical fuel source exploited by malignant cells

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Type 2 diabetes is common in patients with obesity, and obesity increases production of estrogen hormones to abnormal levels, causing further fluctuation in periods and ovulation along with an increased risk of pregnancy complications and miscarriage