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doi:10.1158/1078-0432.CCR-23-1615 Hershman DL, Till C, Shen S, et al

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Post hoc mediation analysis across SURPASS-1 through SURPASS-5 found that decreases in systolic blood pressure (ranging from 1.3 mmHg to 11.5 mmHg across the tirzepatide doses) were primarily mediated through weight loss [91]

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Lower Breast Cancer Incidence in Women Undergoing Breast Imaging McDonalds study included almost 112,000 women ages 45 to 80 with a BMI of 25 or higher who had breast imaging