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Microglia react to injury through morphological changes, increased proliferation, migration to the target, phagocytosis, activation of the NLRP3 inflammasome, and consequently, the release of proinflammatory mediators [198,201]

Nutritional deficiencyparticularly in protein, iron, zinc, and B vitaminsaccelerates this process

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[1] [2] Documentation of injection site reactions, including photographs when appropriate, can help clinicians assess severity and progression