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Conclusion GLP-1RA medications should be considered in all eligible patients with type 2 diabetes whose HbA 1c is not at their individualised target, who have established atherosclerotic cardiovascular disease or who have a compelling need to promote weight loss or minimise hypoglycaemia
GLP-1 receptors (e.g., liraglutide and semaglutide) act through GLP-1 receptors activating intracellular signaling pathways (cAMP/PKA/CREB, PI3K/AKT, and MAPK/ERK) which regulate metabolic, proliferative, and differentiation processes
A vicious circle between insulin resistance and inflammation in nonalcoholic fatty liver disease
Millions more with obesity have lost weight and improved their health
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