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[7] Clinical trial participants: If retatrutide was obtained as part of a clinical trial, the trial protocol will specify a designated returns and disposal process

Patients on newer anticoagulants like direct oral anticoagulants (DOACs) such as apixaban or rivaroxaban face less variability during weight loss, as these drugs are less weight-dependent

The core problem is quality control

Contamination and quality failures represent another risk category

The increase in demand without a corresponding rise in the product's availability creates concern for a potential obstacle as the variety of uses for GLP-1 agonists continues to expand

Future Perspectives/Conclusions In the search for an anti-obesity pharmacotherapeutic which can rival the weight loss effects of bariatric surgery, research and development of gut hormone co-agonists is gaining momentum