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Regarding lactation, there are no data on tirzepatide presence in human milk, effects on the breastfed infant, or effects on milk production

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For example, the term resolved is not synonymous with remission. Clinical Criteria for Diabetes Mellitus in Remission Note* - Remission does not mean cure

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Use in Bipolar Disorder and Psychiatric Conditions Under Investigation Research suggests tamoxifens inhibition of protein kinase C may offer therapeutic benefit in mood stabilization, though definitive data remain limited

However, biweekly dosing represents off-label use not supported by FDA labeling or clinical trial evidence