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Keywords: Obesity, Diabetes, GLP-1 receptor agonist, Depression, Binge-eating disorder, Qualitative Introduction Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of drugs developed initially for treatment of type 2 diabetes (T2D) and then obesity, by mimicking the incretin effect which includes glucose-dependent increased insulin secretion and improved glycaemic control, and inducing weight loss in a dose-dependent manner [1]

This final action has caught the eye of the general public and has pushed GLP-1 agoniststhe most well-known being semaglutideinto the limelight, even among people without diabetes

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Many providers recommend a titration schedule that allows the body to adjust to the medication, potentially improving tolerance

GLP-1 medications offer multiple benefits beyond weight loss: Enhanced insulin sensitivity Reduced inflammation throughout the body Improved blood sugar regulation Slowed gastric emptying, promoting satiety Potential cardiovascular protection Research over the past two years has revealed that GLP-1s are powerful tools for comprehensive metabolic health, not just weight management