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Inform patients of the potential risk for worsening renal function, which in some cases may require dialysis [see Warnings and Precautions (5.5)]

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30 Furthermore, a comparative trial of exenatide and liraglutide in T2DM subjects concluded that both incretin mimetics were associated with a significant reduction in body weight when compared to baseline (2.87 kg and 3.24 kg, respectively)

Guillaume de Lartigue, Ph.D., an assistant professor of pharmacodynamics in the UF College of Pharmacy, said the hormone has received a lot of attention as a gut-brain signaling molecule that can be targeted for treating metabolic diseases

DPP4 is a serine protease that cleaves a dipeptide from the N-terminal side of the incretin hormones adjacent to proline or alanine
