glp-1 for addiction Anti-Obesity Rx and Alcohol and Substance Use Disorders Frontiers | The therapeutic potential
Description
GEP44 mediates insulin-independent glucose uptake in muscle via interactions with Y1-R GEP44 may also reduce serum glucose levels via direct interactions resulting in increased glucose uptake in muscle tissue

However, the health benefits are often even more significant for older individuals because they are at higher baseline risk for obesity-related diseases

Diabetes Ther 14(4):777786 Ceasovschih A, Asaftei A, Lupo MG, Kotlyarov S, Bartuskova H, Balta A et al (2025) Glucagon-like peptide-1 receptor agonists and muscle mass effects

Future research should explore not only who responds to GLP-1 RA pharmacotherapy, but also how to maintain progress once medication ends, especially in vulnerable subgroups

Is appetite suppression enough for a long-term fat loss

This designation was expected to further boost Trulicity sales
