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Coverage Baseline Previously unavailable under Medicare Part D Only 13 states cover them in Medicaid (KFF HMA survey) 19% of large employers cover GLP-1s for obesity, though 43% of employers with 5,000+ employees offer coverage (KFF 2025 survey) Current Expansion ~50% of CVS Caremark clients now provide coverage for weight loss Medicare GLP-1 Bridge program launches coverage for eligible Medicare Part D patients 7/1/26 This aligns with a recent survey from Business Group on Health that found 67% of the surveyed employers now cover GLP-1s for weight loss (though a reduction is expected for 2027)

GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide) are approved for type 2 diabetes and obesity, not Hashimoto's thyroiditis

Diarrhea affects about 30% of users of both medications

The GLP-1 receptor exists in multiple tissues, including immune cells, and theoretical concerns exist about GLP-1 medications potentially modulating immune responses

Microdosing is typically taken once weekly

These scholars reported that GLP-1RAs can promote cell proliferation and survival by activating the P13K and ERK1/2 signaling pathways (75)