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[3],[4] In addition, the traditional role of metformin in the early management of T2D is not always appropriate if not tolerated or contraindicated (eg, eGFR 20-25 mL/min/1.73 m 2

These findings should provide some reassurance with respect to the psychiatric safety of these drugs

[DOI] [PubMed] [Google Scholar] 11.Li L, El-Kholy W, Rhodes CJ, Brubaker PL

It works through multiple mechanisms AMPK activation and bitter taste receptor pathways in the gut and a meta-analysis of 37 RCTs confirms meaningful glucose-lowering effects

The most commonly observed adverse effects in clinical studies are gastrointestinal in nature, consistent with the GLP-1 receptor agonist class

People who take the pills tend to eat less overall