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This rise is usually observed within weeks of therapy initiation

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Important precautions High potassium levels (hyperkalaemia) Spironolactone can cause dangerously high levels of potassium in your blood

Pfizer discontinued the twice-daily formulation in December 2023 due to gastrointestinal side effects and high discontinuation rates

Healthcare providers should educate patients on proper storage during initial prescribing and reinforce these instructions at follow-up visits
