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[DOI] [PubMed] [Google Scholar] 706.Jensen S.L., Holst J.J., Nielsen O.V., Lauritsen K.B

Every 5 kg of weight loss independently reduces systolic blood pressure by approximately 3 to 5 mmHg, reduces triglycerides, improves HDL cholesterol, reduces insulin resistance, decreases systemic inflammation, and reduces mechanical strain on the heart

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Tissue-specific peptide processing occurs through prohormone convertases that produce glucagon in the pancreas and GLP-1 and GLP-2 in the intestine 2

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