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Liraglutide 3.0 mg resulted in an additional 6.2% weight loss from the initial average of 6.0% [42]

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The largest numbers of GLP-1R cells were observed in regions associated with autonomic and behavioural control of energy balance, such as the paraventricular nucleus (PVN), arcuate nucleus (ARC), dorsomedial hypothalamic nucleus (DMH) and central amygdala

Rather than targeting GLP-1 receptors alone, it's a dual agonist activating both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors simultaneously