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IntroductionWith the rise in glucagon-like peptide 1 receptor agonist (GLP-1RA) medication usage for Type 2 diabetes mellitus and weight loss, concerns have ...

And when progress slows, patients look elsewhere

Study results: what did they find

Results showed that in PA-treated HUVECs and HFD-fed ApoE/ mice, combination of metformin and liraglutide at lower dose significantly improved endothelial dysfunction compared with the single treatment

The aim of the present review is to examine the cellular processes underlying the actions of these new, highly significant classes of peptide receptor agonists

and with patients who have taken GLP-1 drugs and experienced widely varying reactions.