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A., Nelson, E

Policymakers often demand robust real-world evidence to justify high expenditures

Via several processes, including insulin and leptin resistance, perivascular adipose tissue dysfunction, reduced kidney function, activation of the renin-angiotensin-aldosterone system, and increased sympathetic nervous system activity, obesity can cause hypertension

So most programs include a basic consult (usually virtual) to establish the need, send you the injections, and simply monitor and maintain your dose until youve either achieved your weight-loss goal, or until youre just tired of injecting yourself

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Their multiple effects beyond glycemic control makes them a valuable addition to the armamentarium of antidiabetic medications