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Description
The current ASA guidelines are based on expert consensus rather than high-quality clinical evidence, and may not adequately address the perioperative risks posed by these medications
When thyroid function tests change, the shifts are usually small and appear to relate to weight loss and broader metabolic changes
These may include shakes or smoothies with yogurt, fruit, and vegetables
Results from a 20-week phase 1b clinical trial showed that a once-weekly dose of 2.4 mg cagrilintide in combination with an equal dose of semaglutide, collectively termed cagrisema, achieved up to 17.1% weight reduction in the obese population
Clinical trials have documented that patients who lose more than 20% of their body weight are at higher risk for hair shedding
Based on our results, we propose that the GLP-1/GLP-1R signalling in the OB constitutes a neuronal pathway involved in regulating energy homeostasis
