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In comparison, older treatments like phentermine-topiramate typically yield lesser results, often achieving only a 5-10% reduction

One clinical trial found semaglutide users maintained higher resting metabolic rates at equivalent weight-loss stages compared to placebo participants
Ann Med

[DOI] [PubMed] [Google Scholar] 5.Zhang Y., Moran A.E

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The Clinical Evidence Phase 2 trials discovered that individuals on retatrutide shed an average of 24% of their initial weight within a 48-week period
