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Knockdown of GMF in BV2 microglia by CRISPR/Cas9 targeting inhibited microglia activation, which resulted in a reduction of the inflammatory burden and an improvement in motor performance (Selvakumar et al., 2019, 2020)

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In one study of 208 patients, 45 experienced 88 fractures, with Standardized Incidence Ratios (SIRs) of 2.9 in females and 3.4 in males