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Even imperfect outcomes from treatment attempts beat untreated obesity

Physical activity: Patients who exercise, particularly with resistance training, typically lose more weight and maintain better body composition

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Some published studies have pointed out that while such drugs help patients lose weight, there is a risk of loss of muscle mass

In conclusion, future large, randomized, placebo-controlled trials are needed to confirm the long-term safety and efficacy profile of semaglutide and tirzepatide used for different purposes in patients with T1D (at different stages of the disease), double diabetes and LADA