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In endurance-trained men, GLP-1 plasma concentrations are elevated immediately at 30 and 45 minutes after exercise

doi: 10.1172/jci200215001

While studying GLP-1s and how effectively they treat diabetes, researchers discovered how significantly these medications can also affect a persons appetite, satiety, and food intake

David Joffe, BSPharm, CDE Tina Burge, PharmD Candidate Florida A&M University Kiet Ngo, Pharm D Candidate Mercer University Abnormalities in incretin hormones such as the glucagon-like peptide-1 (GLP-1) contribute to the development of hyperglycemia

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Unlike injectable GLP-1 receptor agonists, which bypass the stomach, the oral formulation relies on an absorption enhancer to facilitate uptake in the gastrointestinal tract
