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For the next steps in this research, Xu said the team plans to examine if Preclinical and clinical studies are necessary to understand the mechanisms and establish causal effects through randomized trials, she continued

Body fat percentage scales work by using bioelectrical impedance analysis (BIA)

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The SELECT trial showed semaglutide 2.4 mg reduced major cardiovascular events in people with obesity and cardiovascular disease but without diabetes , leading to FDA approval for CV risk reduction in this group

In animal research, giving Akkermansia to mice improved features of diet-induced metabolic problems (Everard et al., 2013), and a small human trial found that pasteurized Akkermansia was safe, well tolerated, and linked to some improved metabolic markers in adults with overweight or obesity (Depommier et al., 2019)