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Description
Wegovy, a brand name of semaglutide, has been associated with these side effects: Nausea and vomiting Diarrhea or constipation Stomach pain or indigestion Decreased appetite leading to weight loss Fatigue and dizziness Increased heart rate Insomnia (difficulty sleeping) In rare cases, patients may also experience: Tremors and feelings of anxiety or nervousness

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Specific modifications at the N-terminal positions one or two resulted in DPP4 resistance that led to enhanced insulin secretion in BRIN-BD11 cells and improvement of glucose tolerance in ob/ob mice

Genetic insights help your provider anticipate which side effects you may experience and tailor your starting dose and titration speed accordingly, potentially reducing diarrhea severity

MGL-1: macrophage galectin-1

[DOI] [PMC free article] [PubMed] [Google Scholar] 147
