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In people with T2D, SUSTAIN-6 revealed increased diabetic-retinopathy complications with semaglutide, primarily in subjects with pre-existing retinopathy and rapid HbA1c reduction 45,46

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Recent developments: April 2026, The FDA proposed excluding semaglutide, tirzepatide, and liraglutide from the 503B bulks list, potentially limiting large-scale compounding activities

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