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"Treatment with semaglutide, at low doses, significantly reduces body weight in almost 80% of obese PCOS patients who were unresponsive to a previous lifestyle plan." Enrico Carmina, Endocrinology Unit, University of Palermo Side Effects and Safety Profile The most common side effects of GLP-1 agonists are gastrointestinal issues, particularly nausea and vomiting, which are more pronounced during dose escalation

Weight loss Weight loss with GLP-1 treatment usually moves at a slower pace to start

However, some side effects can include: Nausea Heartburn Headaches Constipation Diarrhea These side effects are most common when first starting GLP #1 or GLP #2 injections or increasing dosages of these medications

One study with 58 participants recorded the outcomes of people who took 250 or 600 mg of ashwagandha extract for eight weeks

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A decrease in their level directly affects protein synthesis, which leads to a decrease in muscle mass [169]