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However, further research is needed to fully understand how these therapies exert their effect on body weight and in the last section we cover open questions about the potential mechanisms of multiagonist drugs, and the understanding of how gutbrain communication can be leveraged to achieve sustained body weight loss without adverse effects.

Hormone-signaling investigations

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For many people, these medications may reduce appetite, which can make it harder to eat enough protein, calories, vitamins, minerals, and fluids each day