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Tirzepatide (Mounjaro) is a once-weekly GLP-1/GIP medication that may help eligible patients manage appetite, support weight loss, and improve long-term weight management under medical supervision

Managing Cold Sensitivity During GLP-1 Therapy Simple lifestyle adjustments can significantly reduce discomfort from temperature sensitivity

All the research so far, also from the market research firm Circana, shows that those on the drugs eat less, switch to healthier foods and cut their alcohol intake

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Interestingly, these benefits may be blunted in the approximately 30% of patients in whom liraglutide increased the resting heart rate (HR) by 10 bpm or more (61)

The 28-day window already accounts for minor temperature fluctuations within the approved range