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There is also evidence that activation of thermogenesis has other positive impacts on metabolic functions, such as insulin resistance, hyperglycemia, and elevated blood lipids, which may provide other benefits to those on GLP-1RA [80]

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Common Adverse Reactions: Nausea, diarrhea, decreased appetite, vomiting, constipation, dyspepsia, abdominal pain, and injection-site reactions

In TRIUMPH-4, 18.2% of people on the 12 mg dose stopped because of side effects, compared with around 7% on Wegovy in STEP 1