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For example, high-dose weekly semaglutide (2.4 mg) enables around 15% average body-weight reduction over about 16 months rivaling bariatric surgery outcomes in efficacy

The Mayo Clinic's Andres Acosta M.D., Ph.D

According to a joint Advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society, a daily protein intake of 1.21.6 g/kg adjusted body weight, should be considered in individuals initiating GLP-1RA therapy, particularly when caloric restriction is prescribed

But mechanistically, they are not interchangeable with a supplement that may modestly influence some metabolic markers

Drinks like sodas, juices, lattes, and alcohol may seem harmless, but they dont make you feel full

H., et al., GlucagonLike Peptide1 Analogues and Risk of Breast Cancer in Women With Type 2 Diabetes: Population Based Cohort Study Using the UK Clinical Practice Research Datalink, British Medical Journal 355 (2016): i5340