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Pillars 13 , 100162 (2025)

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As a side note, it may be of interest that while the hunger hormone ghrelin appears to counteract (or rather override) the effects of GLP-1 on satiety, the commonly used anti-diabetic drug metformin appears to increase expression of GLP-1 receptors and enhance GLP-1 secretion and sensitivity in both rodents and humans

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In short, liraglutide, GLP-1 receptor agonist, has a direct effect on atherosclerosis lesion formation via promoting pro-resolving M2 macrophages phenotype

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