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The cysteine-rich and glycosylated regions of DPP-4 carry out the non-enzymatic functions, involved in cell signaling, immune regulation, inflammation, and tissue remodeling (Zhong et al., 2013)

and is approved to be used with a reduced calorie diet along with increased physical activity for adults with obesity, or who are overweight and also have weight-related medical problems, to help them lose weight and keep it off

recent data show that children with obesity have a 46% prevalence of OSA when compared with children seen in a general pediatric clinic (33%)

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