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[DOI] [PubMed] [Google Scholar] 54.Orskov C., Holst J.J., Poulsen S.S., Kirkegaard P
If interventions are not started, the increased demand for insulin can overload pancreatic -cells leading to pancreatic -cell failure, decreased insulin secretion, and uncontrolled glycemia (Figure 1)

doi: 10.3233/JAD-180584 239 TaiJLiuWLiYLiLHolscherC

Acute infection and inflammation cause significant changes in tissue metabolism, resulting in severe tissue hypoxia [22]

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Lifestyle modifications can be beneficial for many people experiencing leg discomfort: Regular physical activity : Moderate exercise, such as walking, swimming, or cycling, may help reduce RLS symptoms
