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Citing a lack of "clinical need" to deviate from FDA-approved versions, the agency is proposing to exclude Semaglutide, Tirzepatide, and Liraglutide from the 503B bulks compounding list

Drug Nutrient Depletion: There is a drug mugger effect meaning these medications can deplete some nutrients when youre on them, so its best to restore lost vitamins and minerals if you take a GLP-1 agonist drug like those listed above

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Public consultation drafts are issued, and final guidance embodies a deliberative judgment

If patients havent spent time building healthy habits during their program, weight regain will be more likely when the medication is stopped

It's about maintaining the metabolic rate that keeps weight off long-term
