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If we ignore the intestinal versus pancreatic source of GLP-1 topic and just focus on the fact that GLP-1 regulates insulin secretion by acting directly on -cell GLP-1rs and either directly or indirectly suppresses glucagon then under what circumstance is glucagon important for -cell GLP-1r signaling

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GLP-1 medications can be powerful tools for the right patients, but they should be part of a complete plan, not a shortcut without guidance

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An analogy for the impact of negative pleural pressure during spontaneous respiration on LV function is that of a person jumping over a hurdle

Plain Language Summary Patients with type 2 diabetes mellitus (T2DM) have many treatment options