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Is Semaglutide Effective for Weight Loss for People Without Diabetes

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HEALTH RISK REDUCTION Lower blood pressure, cholesterol, and decrease cardiovascular disease risk

2025b) improve functional capacity and quality of life in people with obesity-related heart failure with preserved ejection fraction, whether or not they have type 2 diabetes

However, some patients report cramping, likely due to indirect factors such as electrolyte disturbances or rapid weight loss rather than direct drug effects