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Safety and Efficacy of DPP4 Inhibitor and Basal Insulin in Type 2 Diabetes: An Updated Review and Challenging Clinical Scenarios

Oral formulations launched this year removed the biggest barrier to adoption

moderate weight loss (25 kg)

Gastrointestinal adverse events were predominantly limited to initial dosing, while dose escalation resulted in lower discontinuation rates owing to these adverse events than among patients who remained on the starting dose
This significant reduction in liver fat content with cotadutide is likely to be due to hepatic glucagon signalling and subsequent upregulation of fatty acid oxidation

GLP-1 receptor agonists are not officially linked to generalized sensitive skin according to FDA prescribing information