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Once inside, they: Reduce neuroinflammation (inhibit NFB, microglial activation) Boost synaptic plasticity (enhance neuron connectivity) Improve glucose uptake (support brain energy metabolism) Local GLP-1 from neurons likely doesnt drive these effectspharmacological action dominates. | 10 comments on LinkedIn

The GLP-1 market has faced supply constraints in recent months as drugs like Ozempic and Wegovy continue to skyrocket in popularity.

However, gastrointestinal side effects related to GLP-1 RA need appropriate clinical management to mitigate risks and maximize the benefits of therapy in people with IBD