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Research participants who followed the gradual escalation protocol in clinical trials achieved an average of 24% total body weight loss by week 48

Tirzepatide produced -20.2% weight loss versus -13.7% for semaglutide

% % % Individual results vary

The LEADER Trial (Once-Daily Liraglutide) The LEADER trial primarily assessed the cardiovascular safety of once-daily liraglutide compared to placebo [26]

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