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10.1038/s41598-019-49364-x [DOI] [PMC free article] [PubMed] [Google Scholar] 22

3 If initial therapy with metformin and lifestyle efforts are not adequate to achieve individualized glycemic targets, the guidelines recommend that patients should progress to dual therapy by adding either another oral agent, basal insulin, or an injectable GLP-1 receptor agonist

2-month minimum commitment and higher-dose pricing increases are not clearly mentioned before intake

Lower concentrations (1-2 mg/mL) mean larger injection volumes, which is slightly less comfortable but significantly easier to measure accurately

What Science Says Doctors use certain prescription medications to help patients lose weight