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People carrying certain variants in the GLP1R (GLP-1 receptor) and GIPR (glucose-dependent insulinotropic polypeptide receptor) genes show different hormone sensitivities and secretion patterns during nutrient restriction

doi:10.1093/brain/awad064 63

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CHO-SNAP-GLP-1R cells were pretreated 100 nM bafilomycin to generate neutral endosomal pH 30 and exposed to 100 nM FITC-agonists for 30 min at 37 C to induce internalization