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They propose based on rodent and monkey studies that this kind of molecule, when administered at high enough doses, may result in weight loss comparable to the weight loss seen with drugs that include GLP-1 as a target, and without the tolerability issues like nausea and vomiting that often come with the approved treatments, according to a peer-reviewed draft paper published this week

Microdosing protocols vary from person to person, but most people start with 0.05mg to 0.25mg per week

If you are over 65 and experiencing increased urination on tirzepatide, proactive hydration and electrolyte management become even more important

We also do not know the impact of these medications on a persons ability to get pregnant if theyre not taking birth control

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