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Poor sleep increases ghrelin (hunger hormone) levels and reduces the appetite-suppressing effects of GLP-1 receptor activation

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Primary care companion to the Journal of clinical psychiatry, 4(1), 30
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Our study demonstrates that STZ-induced DNP led to a significant increase in the serum levels of all three pro-inflammatory cytokines TNF-, IL-1 and IL-6, and our findings align with prior research indicating that uncontrolled hyperglycemia triggers a series of inflammatory responses in STZ-DNP rats [55]

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