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Why are we talking about GLP-1 agonists now

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After approval, Novo Nordisk is required to conduct a pediatric trial in adolescents younger than 18 years of age and to add semaglutide to a 15-year medullary thyroid carcinoma registry that includes all of the long-acting GLP-1 products

Federal law allows states to exclude agents used for weight loss from their Medicaid formularies so covering GLP-1s for obesity is optional, not required

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However, what we know so far is that the greatest utilization of these therapies have been observed in predominantly wealthy communities, which have comparatively lower rates of obesity and associated cardiometabolic conditions. Most of the data on these therapies thus far has been driven by clinical trials, which do not account for disruptions in medication adherence that often occur among everyday people